Bicluster

Bicluster Motifs

Bicluster Genes

Bicluster Conditions

• H37Rv..7H9.roll.replicate.1.x
• H37Rv..7H9.roll.replicate.2.x
• H37Rv..7H9.roll.replicate.3.x
• H37Rv..7H9.roll.replicate.4.x
• H37Rv..7H9.shake.replicate.1
• H37Rv..7H9.shake.replicate.4
• H37Rv..Dubos.media.replicate.1
• H37Rv..Dubos.media.replicate.2
• H37Rv..Sauton.s.media.replicate.2
• H37Rv..Sauton.s.media.replicate.4
• H37Rv..Youman.media.replicate.1
• H37Rv..7H9.roll.replicate.1.y
• H37Rv..7H9.roll.replicate.2.y
• H37Rv..7H9.roll.replicate.3.y
• H37Rv..7H9.roll.replicate.4.y
• Strain.CDC1551..replicate.2
• Strain.CDC1551..replicate.3
• Strain.CDC1551..replicate.4
• Strain.1006...replicate.2
• Strain.1006...replicate.3
• Strain.1254...replicate.4
• Strain.1254...replicate.2
• Strain.1254...replicate.3
• Strain.1254...replicate.1
• Strain.1843..replicate.1
• Strain.1843...replicate.2
• Strain.1843...replicate.3
• Strain.3160..replicate.2
• Strain.3160...replicate.3
• Strain.3160..replicate.4
• Strain.9700665..replicate.1
• Strain.9700665..replicate.3
• Strain.9800608..replicate.1
• Strain.9800608..replicate.2
• Strain.9800608...replicate.3
• Strain.9802501..replicate1
• Strain.9802501..replicate.2
• Strain.9802501..replicate.3
• Strain.9802501..replicate.4
• Strain.9802826..replicate.1
• Strain.9802826..replicate.2
• Strain.9802826..replicate.3
• Strain.9802826..replicate.4
• Strain.M3061a..replicate.2
• Strain.M3061a..replicate.3
• H37Rv.Day.0.rep.1
• H37Rv.Vs.M.bovis.rep1
• H37Rv.Vs.M.bovis.rep4
• MTB.strain.1254.Ctrl.vs.0.005.mM.DETA.NO.40min.rep.2.x
• MTB.strain.1254.Ctrl.vs.0.005.mM.DETA.NO.40min.rep.3.x
• MTB.strain.1254.Ctrl.vs.0.005.mM.DETA.NO.40min.rep.4.x
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.1.x
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.3.x
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.6.x
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.5min.rep.4
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.20min.rep.2
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.40min.rep.1.x
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.40min.rep.2.x
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.1hr.rep.4
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.8hrs.rep.1
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.8hrs.rep.4
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.16hrs.rep.1
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.16hrs.rep.4
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.24hrs.rep.1
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.24hrs.rep.2
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.24hrs.rep.3
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.24hrs.rep.4
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.1.x
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.2.x
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.3.x
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.4.x
• H37Rv.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.4
• CDC1551.Ctrl.vs.0.05.mM.DETA.NO.40.min.rep.4
• MTB1254.Day.0.rep.2
• MTB1254.Day.0.rep.3
• MTB.strain.1254.Ctrl.vs.2hr.Hypoxia.rep.2
• MTB1254.vs..MTB1254.rep2
• MTB1254.vs..MTB1254.rep3
• H37Rv.hypoxia.2hr.rep.1
• H37Rv.hypoxia.2hr.rep.3
• H37Rv.hypoxia.2hr.rep.4
• H37Rv.Day.0.rep.3
• H37Rv.Day6.1
• H37Rv.Day6.2
• H37Rv.Day6.3
• H37Rv.Day8.1
• H37Rv.Day8.2
• H37Rv.Day8.3
• H37Rv.Day14.3
• H37Rv.Day24.1
• H37Rv.Day24.3
• H37Rv.Day60.1
• H37Rv.Day60.2
• NRP.Day6..1
• NRP.Day6..2
• NRP.Day6..3
• NRP.Day8..3
• NRP.Day10..2
• NRP.Day10..3
• NRP.Day12..2
• NRP.Day12..3
• NRP.Day14..1
• NRP.Day14..3
• NRP.Day14..6
• NRP.Day14..7
• NRP.Day20..1
• NRP.Day20..2
• NRP.Day30..1
• WT.t.6h.WT.t.0h..2
• WT.t.0h.WT.t.6h..2
• X0.1mM.GSNO.DMSO..3.5h
• X0.1mM.GSNO.DMSO..6h
• X0.1mM.GSNOvsDMSO..6h.
• X0.1mM.GSNOvsDMSO..6h.A
• X4mM.H2O2vsctrl..2h.
• X4mM.H2O2.ctrl..4h...1
• X4mM.H2O2.ctrl..4h...2
• X4mM.H2O2vsctrl..4h.
• X4mM.H2O2vsctrl..4h.A
• H2O2.4mM.vs.ctrl.8h.1
• X25J.UV.ctrl..2h.
• X25J.UVvs.ctrl..6h.
• UV.40J.vs.ctrl.8h.1
• X60J.UV.ctrl..2h.
• X60J.UVvsctrl..6h.
• UV.60J.vs.ctrl.6h.1
• H37Rv.hypoxia.4hr.rep.3
• H37Rv.hypoxia.4hr.rep.4
• H37Rv.hypoxia.4hr.rep.6
• H37Rv.hypoxia.8hr.rep.1
• H37Rv.hypoxia.8hr.rep.2
• H37Rv.hypoxia.8hr.rep.3
• H37Rv.hypoxia.12hr.rep.1
• H37Rv.hypoxia.12hr.rep.2
• H37Rv.hypoxia.1.day.rep.2
• H37Rv.hypoxia.1.day.rep.3
• H37Rv.hypoxia.1.day.rep.4
• H37Rv.hypoxia.4.day.rep.3
• H37Rv.hypoxia.4.day.rep.7
• H37Rv.hypoxia.7.day.rep.1
• H37Rv.hypoxia.7.day.rep.2
• H37Rv.hypoxia.7.day.rep.3
• H37Rv.hypoxia.7.day.rep.4
• H37Rv.hypoxia.7.day.rep.7
• H37Rv.cDNA.Cy3.vs.H37Rv.gDNA.Cy5..DS..rep.3
• H37Rv.cDNA.Cy5.vs.H37Rv.gDNA.Cy3.rep.3
• Strain.27.cDNA.Cy5.vs.H37Rv.gDNA.Cy3.rep.1
• Strain.32.cDNA.Cy3.vs.H37Rv.gDNA.Cy5..DS..rep.2
• Strain.49.cDNA.Cy3.vs.H37Rv.gDNA.Cy5..DS..rep.1
• Strain.49.cDNA.Cy3.vs.H37Rv.gDNA.Cy5..DS..rep.2
• Strain.49.cDNA.Cy3.vs.H37Rv.gDNA.Cy5..DS..rep.3
• H37Rv.wild.type.Vs.H37Rv.wild.type.rep.1
• H37Rv.wild.type.Vs.H37Rv.wild.type.rep.3
• H37Rv.wild.type.Vs.H37Rv.wild.type.rep.4
• H37Rv.wild.type.control.vs.5mM.Diamide.for.60.min.rep.5
• H37Rv.grown.in.7H9.vs.H37Rv.4hrs.after.infection.in.macrophages.rep.1
• H37Rv.grown.in.7H9.vs.H37Rv.4hrs.after.infection.in.macrophages.rep.3
• H37Rv.grown.in.7H9.vs.H37Rv.4hrs.after.infection.in.macrophages.rep.4
• H37Rv.grown.in.7H9.vs.H37Rv.4hrs.after.infection.in.macrophages.rep.5
• H37Rv.grown.in.7H9.vs.H37Rv.24hrs.after.infection.in.macrophages.rep.2
• H37Rv.grown.in.7H9.vs.H37Rv.24hrs.after.infection.in.macrophages.rep.3
• H37Rv.grown.in.7H9.vs.H37Rv.24hrs.after.infection.in.macrophages.rep.4
• H37Rv.grown.in.7H9.vs.H37Rv.24hrs.after.infection.in.macrophages.rep.5
• AA_10uM_10min_01
• AA_30uM_10.min_04
• AA_30uM_1h_04
• AA_30uM_2h_03
• AA_30uM_2h_04
• AA_30uM_2h_05
• AA_30uM_2h_06
• AA_30uM_30min_01
• AA_30uM_30min_03
• AA_30uM_30min_04
• AA_30uM_30min_05
• AA_30uM_30min_06
• AA_30uM_30min_07
• AA_30uM_30min_08
• AA_30uM_30min_09
• AA_30uM_4h_01
• AA_30uM_4h_03
• AA_30uM_4h_04
• AA_30uM_4h_07
• AA_30uM_4h_08
• AA_3uM_10.min_01
• AA_3uM_10min_02
• AA_60uM_24h_02
• AA_60uM_24h_03
• CHP_25uM_1h_01
• CHP_25uM_2h_01
• L2A_30uM_10min_05
• L2A_30uM_10min_07
• L2A_30uM_10min_08
• L2A_30uM_1h_01
• L2A_30uM_1h_03
• L2A_30uM_1h_04
• L2A_30uM_1h_06
• L2A_30uM_2h_01
• L2A_30uM_2h_02
• L2A_30uM_2h_03
• L2A_30uM_2h_05
• L2A_30uM_30min_01
• L2A_30uM_30min_02
• L2A_30uM_30min_04
• L2A_30uM_30min_05
• L2A_30uM_4h_03
• L2A_30uM_4h_05
• LAA_50uM_10min_02
• OA_50uM_10min_02
• OA_50uM_10min_04
• OA_50uM_10min_05
• OA_50uM_10min_06
• OA_50uM_10min_08
• OA_50uM_1h_04
• OA_50uM_1h_06
• OA_50uM_1h_07
• OA_50uM_1h_08
• OA_50uM_1h_09
• OA_50uM_24h_03
• OA_50uM_2h_01
• OA_50uM_2h_03
• OA_50uM_2h_04
• OA_50uM_2h_05
• OA_50uM_2h_06
• OA_50uM_2h_07
• OA_50uM_2h_08
• OA_50uM_2h_10
• OA_50uM_30min_01
• OA_50uM_30min_02
• OA_50uM_30min_03
• OA_50uM_30min_05
• OA_50uM_30min_08
• OA_50uM_4h_01
• OA_50uM_4h_02
• OA_50uM_4h_03
• OA_50uM_4h_04
• OA_50uM_4h_06
• OA_50uM_4h_07
• PA_100uM_24h_01
• PA_100uM_2h_03
• PA_100uM_2h_04
• PA_10uM_10.min_01
• PA_10uM_10min_02
• PA_50uM_10.min_02
• PA_50uM_10min_01
• PA_50uM_10min_07
• PA_50uM_10min_09
• PA_50uM_10min_10
• PA_50uM_12h_01
• PA_50uM_1h_04
• PA_50uM_1h_05
• PA_50uM_1h_06
• PA_50uM_1h_09
• PA_50uM_1h_10
• PA_50uM_24h_07
• PA_50uM_24h_08
• PA_50uM_2h_04
• PA_50uM_2h_06
• PA_50uM_2h_08
• PA_50uM_30.min_06
• PA_50uM_30min_01
• PA_50uM_30min_02
• PA_50uM_30min_10
• PA_50uM_3d_06
• PA_50uM_4h_03
• PA_50uM_4h_06
• PA_50uM_4h_07
• PA_50uM_8h_01
• PA_50uM_8h_02
• PA_50uM_8h_03
• PA_50uM_8h_05
• PA_50uM_8h_06
• PA_5uM_10.min_01
• Starvation_1254_12h_01
• Starvation_1254_12h_02
• Starvation_1254_12h_03
• Starvation_1254_12h_04
• Starvation_1254_24h_07
• Starvation_1254_3d_02
• Starvation_1254_3d_03
• Starvation_1254_5d_02
• Starvation_1254_6h_02
• Starvation_1254_6h_03
• Starvation_1254_6h_05
• Starvation_1254_6h_07
• Starvation_1254_6h_08
• H37Rv.control.vs.1mg.ml.cholesterol.for.24.hrs.rep.2
• H37Rv.control.vs.1mg.ml.cholesterol.for.24.hrs.rep.3
• CDC1551.Ctrl.vs.clinical.isolate.10514.01_Afri2.rep.3
• CDC1551.Ctrl.vs.clinical.isolate.10517.01_Afri2.rep.3
• CDC1551.Ctrl.vs.clinical.isolate.1500.03_Beijing.rep.2
• CDC1551.Ctrl.vs.clinical.isolate.2199.99_Uganda.rep.1
• CDC1551.Ctrl.vs.clinical.isolate.2199.99_Uganda.rep.3
• CDC1551.Ctrl.vs.clinical.isolate.2333.99_Uganda.rep.1
• CDC1551.Ctrl.vs.clinical.isolate.2333.99_Uganda.rep.2
• CDC1551.Ctrl.vs.clinical.isolate.2333.99_Uganda.rep.3
• CDC1551.Ctrl.vs.clinical.isolate.2336.02_Haarlem.rep.1
• CDC1551.Ctrl.vs.clinical.isolate.4130.02_Haarlem.rep.1
• CDC1551.Ctrl.vs.clinical.isolate.4130.02_Haarlem.rep.3
• CDC1551.Ctrl.vs.clinical.isolate.4850.03_EAI.rep.3
• CDC1551.Ctrl.vs.clinical.isolate.5468.02_Afri2.rep.1
• CDC1551.Ctrl.vs.clinical.isolate.947.01_EAI.rep.2
• Clinical.isolate.10514.01_Afri2.extra.vs.intracellular.in.activated.macrophages.rep.2
• Clinical.isolate.10517.01_Afri2.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.10517.01_Afri2.extra.vs.intracellular.in.activated.macrophages.rep.2
• Clinical.isolate.1500.03_Beijing.extra.vs.intracellular.in.activated.macrophages.rep.2
• Clinical.isolate.1797.03_EAI.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.1934.03_Beijing.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.2169.99_Uganda.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.2336.02_Haarlem.extra.vs.intracellular.in.activated.macrophages.rep.2
• Clinical.isolate.4130.02_Haarlem.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.4130.02_Haarlem.extra.vs.intracellular.in.activated.macrophages.rep.2
• Clinical.isolate.5468.02_Afri2.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.947.01_EAI.extra.vs.intracellular.in.activated.macrophages.rep.1
• Clinical.isolate.9532.03_Haarlem.extra.vs.intracellular.in.activated.macrophages.rep.2
• H37Rv.extra.vs.intracellular.in.activated.macrophages.rep.1
• H37Rv.extra.vs.intracellular.in.activated.macrophages.rep.2
• CDC1551.extra.vs.intracellular.in.activated.macrophages.rep.1
• BCG.2hr.phagosomal.profile
• BCG.24hr.phagosomal.profile
• M..tuberculosis.CDC1551.2hr.phagosome.expression.profile
• M..tuberculosis.CDC1551.24hr.phagosome.expression.profile
• MTB.in.Wild.type.macrophages...IFNg.for.4hrs
• MTB.strain.1254.Ctrl.vs.0.005.mM.DETA.NO.40min.rep.2.y
• MTB.strain.1254.Ctrl.vs.0.005.mM.DETA.NO.40min.rep.4.y
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.2
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.3.y
• MTB.strain.1254.Ctrl.vs.0.05.mM.DETA.NO.40min.rep.6.y
• MTB.strain.1254.Ctrl.vs.0.05.mM.H202.40min.rep.2
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.40min.rep.2.y
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.40min.rep.5
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.40min.rep.7
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.4hrs.rep.2
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.4hrs.rep.3
• MTB.strain.1254.Ctrl.vs.0.5.mM.DETA.NO.4hrs.rep.4
• MTB.strain.1254.Ctrl.vs.0.5.mM.H202.40min.rep.1
• MTB.strain.1254.Ctrl.vs.0.5.mM.H202.40min.rep.5
• MTB.strain.1254.Ctrl.vs.0.5.mM.H202.40min.rep.6
• MTB.strain.1254.Ctrl.vs.1.0.mM.DETA.NO.40min.rep.2.y
• MTB.strain.1254.Ctrl.vs.1.0.mM.DETA.NO.40min.rep.4.y
• MTB.strain.1254.Ctrl.vs.200.mM.H202.40min.rep.1
• MTB.strain.1254.Ctrl.vs.200.mM.H202.40min.rep.4
• MTB.strain.1254.Ctrl.vs.200.mM.H202.40min.rep.5
• MTB.strain.1254.Ctrl.vs.200.mM.H202.40min.rep.6
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.3.y
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.4.y
• MTB.strain.1254.Ctrl.vs.5.0.mM.DETA.NO.40min.rep.1.y
• MTB.strain.1254.Ctrl.vs.5.0.mM.H202.40min.rep.5
• MTB.strain.1254.Ctrl.vs.5.0.mM.H202.4hr.rep.3
• MTB.strain.1254.Ctrl.vs.50.0.mM.H202.40min.rep.1
• MTB.strain.1254.Ctrl.vs.50.0.mM.H202.40min.rep.2
• MTB.strain.1254.Ctrl.vs.50.0.mM.H202.40min.rep.3
• MTB.strain.1254.Ctrl.vs.50.0.mM.H202.40min.rep.5
• MTB.strain1254.vs.MTB.strain.1254.for.DETA.NO.exp.control.rep.2
• MTB.strain1254.vs.MTB.strain.1254.for.DETA.NO.exp.control.rep.3
• MTB.strain1254.vs.MTB.strain.1254.for.DETA.NO.exp.control.rep.4
• Russell_Lab_Spotted_Oligos_1.1..14.day.resting.macrophage.infection.2hr..rep.1..Russell_Lab_Spotted_Oligos_1.1..
• Russell_Lab_Spotted_Oligos_1.4..14.day.resting.macrophage.infection.Day.2..rep.2..Russell_Lab_Spotted_Oligos_1.4..
• Russell_Lab_Spotted_Oligos_1.9..14.day.resting.macrophage.infection.Day.8..rep.1..Russell_Lab_Spotted_Oligos_1.9..
• SG2.A0_N02A01c3
• SG2.D0_N02A01c5
• SG6.G0_N5A02cy.5
• SG6_A0_N7A10cy.3
• SG6_B0_N7A10cy.5
• SG7.AT0_N11A01cy.5
• SG8.A.Day.0.pre_fix_N37A04cy.5
• SG8.C.Day.0.pre_N27A07cy.3
• SG8.C.Day.1_N37A11cy.5
• SG8.C.Day.1_N27A09cy.3
• SG8.D.Day.1_N27A12cy.3
• SG8.B.Day.1_N37A05cy.5
• SG8.A.Day.1_fix_N37A03cy.5
• SG7.CT1_N11A07cy.5
• SG7.BT1_N11A06cy.5
• SG6_B1_N7A11cy.5
• SG6_A1_N7A11cy.3
• SG6.D1_N5A05cy.5
• SG6.C1_N5A04cy.5
• SG2.D1_N02A02c5
• SG8.C.Day.2_N37A12cy.5
• SG8.B.Day.2_N37A06cy.5
• SG2.A2_N02A03c3
• SG2.B2_N02A11c3
• SG2.D2_N02A03c5
• SG8.A.Day.3_N37A09cy.3
• SG8.B.Day.3_N37A07cy.5
• SG2.A3_N02A04c3
• SG2.D3_N02A04c5
• SG2.A5_N02A05c3
• SG2.D5_N02A05c5
• SG6D.T7_N11A02cy.3
• SG6_A7_N7A12cy.3
• SG7.T7C_N11A10cy.5
• SG7.T7D_N11A11cy.5
• SG8.B.Day.7_N37A09cy.5
• SG8.A.Day.7_N37A11cy.3
• SG.ISB.3.7A_N30A02cy.5
• SG.ISB.3.7B_N30A03cy.3
• SG.ISB.3.7C_N30A03cy.5
• SG12.C0_N32A05cy.5
• SG12.B0_N32A09cy.3
• SG12.B6_N32A01cy.5
• SG12.C24_N32A11cy.5
• SG12.B24_N32A03cy.5
• SG2.A8_N02A07c3
• SG2.B8_N02A11c5
• SG2.D8_N02A07c5
• SG6.C8_N5A08cy.5
• SG6.B8_N5A07cy.5
• SG6.A8_N5A06cy.5
• SG7.T8B_N11A06cy.3
• SG7.T8D_N11A08cy.3
• SG.ISB.3.8A_N30A04cy.5
• SG.ISB.3.8B_N30A05cy.3
• SG.ISB.3.8D_N30A06cy.3
• SG2.A9_N02A08c3
• SG2.B9_N02A12c5
• SG2.D9_N02A08c5
• SG6.C11_N5A12cy.5
• SG.ISB.3.12C_N30A07cy.5
• SG6.B14_N8A11cy.5
• SG6.C14_N8A12cy.5
• WT_140mM_NaCl_Rep3
• wild.type..mc.2.6020...biological.rep2
• hip.mutant.KL2825..biological.rep2
• hip.mutant.KL2849..biological.rep1
• hip.mutant.KL2849..biological.rep2
• hip.mutant.HTS1090..biological.rep2
• hip.mutant.HTS1105..biological.rep2
• hip.mutant.HT1116..biological.rep2
• hip.mutant.HT1117..biological.rep1
• hip.mutant.HT1130..biological.rep2
• hip.mutant.HT1134..biological.rep1
• hip.mutant.HT1134..biological.rep2
• hip.mutant.HT1137..biological.rep1
• hip.mutant.HT1137..biological.rep2
• hip.mutant.HT1170..biological.rep1
• hip.mutant.HT1170..biological.rep2
• A00470_Q2_t60_diamide
• A00470_Q3_t90_diamide
• A00437_Q1_t30_diamide
• A00437_Q2_t60_diamide
• A00437_Q3_t90_diamide
• A00436_Q1_t30_diamide
• A00436_Q2_t60_diamide
• A00436_Q3_t90_diamide